Summary: (from NCBI-Entrez) ..[read more]This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular
Shimizu K, et al. (J Biol Chem. 1999) provided the physical evidence that mouse jagged1 interacts with notch2 and other notch receptors, indicating that mJagged1 is a ligand for multiple Notch receptors.