|Ligand FGF1 - FIBROBLAST GROWTH FACTOR 1 (ACIDIC) ISOFORM ...[read more..]|
|Ligand FGF4 - FIBROBLAST GROWTH FACTOR 4 PRECURSOR[read more..]| Bellosta P., et al. (Mol Cell Biol, 2001)
identified the receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis, found FGF4 can bind and activate all FGF receptor members, FGFR1, FGFR2, FGFR3 and FGF4.
|Ligand FGF8 - FIBROBLAST GROWTH FACTOR 8[read more..]| Kouhara H, et al. (Oncogene, 1994)
transfected an expression vector encoding a variant form of FGF receptor-1 cloned from SC-3 cells into FGF receptor-negative L6 cells and observed AIGF-dependent inhibition of differentiation. These results demonstrate that the ability of androgen to elicit transformed phenotype of SC-3 cells is mediated through AIGF induction and its interaction with FGF receptor-1.
|Ligand FGF3 - FIBROBLAST GROWTH FACTOR 3 PRECURSOR[read more..]|
Fgf3 was shown to bind with high affinity to the IIIb isoforms of Fgf receptor (FgfR) 1 and FgfR2 and with a lower affinity to the IIIc variant of FgfR2 (Mathieu et al. 1995)