Summary: (from NCBI-Entrez) ..[read more]The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors
McAllister G, et al. (Mol Pharmacol. 2000) developed and used a functional heterologous assay system to find out lysophosphatidic acid as an endogenous ligand for the hEdg2 receptor.The ligand is produced through phosphatidic acid-selective phospholipase A1.