Synonyms:TLR5_HUMAN, Toll-like receptor 5 precursor (Toll/interleukin-1 receptor- like protein 3)
links:Entrez Gene, Omim
Summary: (from NCBI-Entrez) ..[read more]This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are express
TLR5 expression in humans has mainly been shown for intestinal epithelial cells, dendritic cells, and monocytes. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 (Hayashi et al. 2001).