Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin l
Osteoprotegerin (OPG; TNFRSF11B) also known as osteoclastogenesis inhibitory factor (OCIF), is a secreted member of the TNFR family. OPG is a decoy receptor of RANKL and inhibits osteoclast maturation (Ito et al. 2002).