Synonyms:CD36 ANTIGEN-LIKE 1, CD36L1|CD36 AND LIMPII ANALOGOUS 1, CLA1|SCAVENGER RECEPTOR, CLASS B, TYPE I, SRBI, SRB1 SCARB1
links:Entrez Gene, Omim
Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2
Shiratsuchi A et al. (J Biol Chem. 1997) firstly found that phosphatidylserine and probably other acidic phospholipids, which are normally localized in the inner leaflet of the plasma membrane, translocate to the outer leaflet and serve as a signal for phagocytosis by Sertoli cells. Kawasaki Y, et al. (J Biol Chem, 2002) confirmed that SR-BI is a phagocytosis-inducing phosphatidylserine (PS) receptor of Sertoli cells.