Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor gr
Gao AG, et al. (J Biol Chem. 1996) reported that CD47 is a receptor for the C-terminal domain of thrombospondin. Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior.