ICAM1 - INTERCELLULAR ADHESION MOLECULE 1 (CD54), HUMAN RHINOVIRUS RECEPTORFamily:ICAM
Synonyms:CD54|SURFACE ANTIGEN OF ACTIVATED B CELLS, BB2, BB2|ANTIGEN IDENTIFIED BY MONOCLONAL ANTIBODY BB2 ICAM1
links:Entrez Gene, Omim
Summary: (from NCBI-Entrez) ..[read more]This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by Ref
Interplay between rolling and firm adhesion elucidated with a cell-free system engineered with two distinct receptor-ligand pairs.Eniola AO et al. . The interaction between integrin lymphocyte function-associated antigen-1 (LFA-1) and its ligand intercellular adhesion molecule-1 (ICAM-1) is critical in immunological and inflammatory reactions,The extracellular domains of LFA-1 are composed of the large and complex αL and β2 subunits (Song et al. 2005).