Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene is a G protein-coupled receptor whose expression can be induced by phytohemagglutinin. The encoded integral membrane protein is a receptor for the 17 aa neuropeptide nociceptin/orphanin FQ. This gene may be involved in the
Reinscheid RK, et al. (Science.,1995) reported that orphanin FQ is a neuropeptide for an opioidlike G protein-coupled receptor.Nociceptin/orphan FQ, a neuropeptide of 17 amino acids, is derived from a larger precursor, prepronociceptin (PNOC).