Summary: (from NCBI-Entrez) ..[read more]This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal tr
Liaw CW, et al. (Endocrinology. 1996 ) cloned two CRH receptors and the CRF- and sauvagine-induced accumulation of intracellular cAMP could be competitively inhibited by the CRF receptor antagonist D-Phe-CRF.